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临床试验/NCT07519785
NCT07519785已完成不适用

Prognostic Value of the Platelet to Lymphocyte Ratio on Cardiovascular Complications in Chronic Hemodialysis Patients

Minia University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年1月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
试验地点
1
主要终点
to determine if Platelet to Lymphocyte Ratio could be of prognostic value on cardiovascular complications in chronic hemodialysis patients

研究概览

简要总结

Prognostic value of platelet to lymphocyte ratio on cardiovascular complications in chronic hemodialysis patients this study was done to determine the prognostic value of PLR on cardiovascular complications like vascular calcifications and atherosclerosis in carotid and coronary arteries in chronic hemodialysis patients

详细描述

Prognostic value of platelet to lymphocyte ratio on cardiovascular complications in chronic hemodialysis patients this study was done to determine the prognostic value of PLR on cardiovascular complications like vascular calcifications and atherosclerosis in carotid and coronary arteries as these complications are common and well-known causes of morbidity and mortality in chronic hemodialysis patients

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients undergoing hemodialysis for more than 3 months who agreed to be included in the study

排除标准

  • We are going to exclude patients who have:
  • Younger than 18 year- old or Older than 75 year-old,
  • Patients with positive serum marker of anti-hepatitis C virus (anti-HCV), hepatitis B surface antigen (HBsAg) and human immunodeficiency virus (HIV).
  • Alcohol or illicit drug abusers.
  • Inflammatory state due to infection,

研究组 & 干预措施

disease group

60 patients of ESKD on maintenance hemodialysis were investigated for platelet to lymphocyte ratio, S.PTH , S.Ca , S.Phosp Echocardiography and carotid duplex

Healthy control group

20 healthy persons were investigated for platelet to lymphocyte ratio to be compared with the disease group results

结局指标

主要结局

to determine if Platelet to Lymphocyte Ratio could be of prognostic value on cardiovascular complications in chronic hemodialysis patients

时间窗: 6 months

to determine if Platelet to Lymphocyte Ratio could be of prognostic value on cardiovascular complications in chronic hemodialysis patients

To evaluate the association between platelet-to-lymphocyte ratio and cardiovascular complications in patients on chronic maintenance hemodialysis.

时间窗: 6 months

Primary Outcome Association between PLR and cardiovascular complications in chronic hemodialysis patients. Secondary Outcomes optimal PLR cutoff for cardiovascular complication prediction relation of PLR to individual cardiovascular diagnoses relation of PLR to cardiovascular hospitalization relation of PLR to cardiovascular mortality

次要结局

未报告次要终点

研究者

发起方
Minia University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hanaa Mohammad Aly

Nephrology Resident at Elminya Insurance Hospital

Minia University

研究点 (1)

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