Presentation and Outcomes of Acute Appendicitis During COVID Pandemic

Not Applicable

Completed

• Conditions: Acute Appendicitis
• Interventions: Procedure: appendectomy

• Registration Number: NCT05104346
• Lead Sponsor: Mansoura University

Brief Summary

Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world \[1\]. The lifetime risk of developing AA is estimated to be about 8% \[1-3\]. The severe acute respiratory syndrome SARS-CoV-2 Coronavirus (COVID-19) pandemic has raised difficult situations for healthcare systems and organizations around the world, with direct and indirect implications for patient care delivery. COVID-19 causes a wide range of clinical symptoms, including fever, dry cough, myalgia, and exhaustion, with pulmonary involvement in many cases. According to the World Health Organization (WHO), The effect of the COVID-19 pandemic on acute appendicitis and surgical care is unknown due to a lack of evidence. To see how appendicitis care has changed as a result of the COVID-19 pandemic, this study compares clinical presentation, investigative modalities, treatment procedures, and outcomes before and after the pandemic.

Detailed Description

Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world \[1\]. The lifetime risk of developing AA is estimated to be about 8% \[1-3\]. The SARS-CoV-2 Coronavirus (COVID-19) pandemic has raised difficult situations for healthcare systems and organizations around the world, with direct and indirect implications for patient care delivery. COVID-19 causes a wide range of clinical symptoms, including fever, dry cough, myalgia, and exhaustion, with pulmonary involvement in many cases. According to the World Health Organization (WHO), The effect of the COVID-19 pandemic on acute appendicitis and surgical care is unknown due to a lack of evidence. To see how appendicitis care has changed as a result of the COVID-19 pandemic, this study compares clinical presentation, investigative modalities, treatment procedures, and outcomes before and after the pandemic. This is a multicenter prospective cohort study that was conducted for patients presented with Acute Appendicitis (AA).

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2019-03-31
• Primary Completion: 2021-03-31
• Study Completion: 2021-10-01
• Study First Submitted: 2021-10-31
• Status Verified: 2021-11
• Study First Submitted QC: 2021-11-01
• Last Update Submitted: 2021-11-01
• Study First Posted: 2021-11-03
• Last Update Posted: 2021-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1945

Inclusion Criteria

patients with acute appendicitis

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Exclusion Criteria

• patients with acute appendicitis less than 12 years
• malignant appendix

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients in group II (G2) had AA during COVID	appendectomy	patients in group II (G2) had AA during COVID
Patients in group I (G1) had AA prior to the era of COVID	appendectomy	Patients in group I (G1) had AA prior to the era of COVID

Primary Outcome Measures

Name	Time	Method
the management strategy used	one month	the management strategy used, which included conservative or surgical management (open or laparoscopic).

Secondary Outcome Measures

Name	Time	Method
clinical presentation	one month	Alverado score from 1 to 10 the worst score is 10
postoperative complications	one month	postoperative complications have been classified by Dindo G1 TO G5
the negative appendicectomy rate.	one month	This is normal appendix after appendectomy

Trial Locations

Locations (1)

Ayman El Nakeeb; 🇪🇬 Mansoura, Egypt