The efficacy and safety of cineole during long term treatment of patients with asthma

Phase 3

Completed

• Conditions: Asthma; Respiratory

• Registration Number: ISRCTN90948816
• Lead Sponsor: MKL Institute of Clinical Research (MKL Institut für Klinische Forschung GmbH) (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2009-01-28
• Study Start: 2009-05-11
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

1. Patients with asthma for at least two years
2. Reversibility of greater than 15% after inhalation of beta-agonists
3. Aged greater than or equal to 18 and less than or equal to 70 years, either sex

Exclusion Criteria

1. Chronic obstructive pulmonary disease (COPD)
2. Co-medication with other mucolytics
3. Infection at the beginning of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite scores of lung function parameters, asthma symptoms and quality of life. Assessments were initial visit and after 1, 2, 3, 4, 5 and 6 months.

Secondary Outcome Measures

Name	Time	Method
<br> 1. Lung function (spirometry)<br> 2. Asthma symptoms (dyspnoea, secretion, cough)<br> 3. Quality of life (Asthma Questionnaire of Quality of Life [AQLQ])<br><br> Assessments were initial visit and after 1, 2, 3, 4, 5 and 6 months.<br>