Verification of the effectiveness of ovarian reserve assessment using optical coherence tomography (SS-OCT)
Not Applicable
- Conditions
- Malignant disease, Cancer, Breast cancer, Hematologial disease, Leukemia, pediatric cancer
- Registration Number
- JPRN-UMIN000053312
- Lead Sponsor
- St. Marianna University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
If the patient or family has expressed opposition to donating the tissue to research at the time of ovarian tissue freezing. If patient consent is not obtained for ovarian tissue to be performed.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We will image the follicle using OCT and create a standard image. Follicle number counting by OCT (primordial follicle, primary follicle, secondary follicle, antral follicle) Correlation with ovarian histological examination, blood AMH level, and other ovarian reserve tests
- Secondary Outcome Measures
Name Time Method We will also verify whether it is possible to confirm the presence or absence of malignant tumors. In cases where ovarian tissue transplantation is performed, the period until ovarian function recovers after ovarian transplantation, the number of oocytes obtained after ovarian transplantation, fertilization rate, and clinical pregnancy rate (confirmation of gestational sac) are evaluated. If animal experiments are conducted, evaluation items include ovarian function recovery rate, recovery period, number of oocytes collected, and abnormality of oocytes (a separate application will be submitted as an animal experiment).