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临床试验/NCT01912794
NCT01912794Unknown不适用

Postural Responses to External Perturbation in Post-Stroke: Sensorimotor Integration and Rehabilitation

University of Sao Paulo1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2013年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
24
试验地点
1
主要终点
Displacement amplitude of the CP to the anterior-posterior and medial-lateral

研究概览

简要总结

To maintain stable body balance in daily activities, the ability to respond to external perturbations is an essential factor. Such capacity is limited in pathological conditions, such as in stroke, in which postural control is impaired due to lesions to the central nervous system. Impairment to postural control increases body sway during upright posture and leads to augmented frequency of falls. In this sense, the identification of mechanisms involved in body balance disorders after stroke is particularly important in situations of postural perturbation. The purpose of this project is to evaluate reactive postural responses to unpredictable external perturbations, analyzing postural dysfunctions caused by lesion to different brain areas as a result of stroke, and test principles of dynamic body balance rehabilitation.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
45 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Inclusion criteria are as follows. Healthy participants: absence of detectable neurological or physical malfunction which might affect postural control, no use of drugs affecting body balance and preserved mental capacity. Stroke patients: capacity to sustain independently orthostatic posture for at least 5 min. and preserved mental capacity.

排除标准

  • •Exclusion Criteria are: no orthopedic malfunction, no clinical instability associated with systemic disease, no use of drugs affecting body balance and presence of "pusher syndrome".

研究组 & 干预措施

Sensory Conditions

Experimental

干预措施: Sensory Intervention (Other)

结局指标

主要结局

Displacement amplitude of the CP to the anterior-posterior and medial-lateral

时间窗: 2 months

This outcome measure quantified by the difference between the maximum values of the anterior-posterior and medial-lateral after the start of trial and average position in the axis anteroposterior and mediolateral, respectively, in the 200 ms prior to the onset of the trial.

次要结局

  • Coordination between the hip and ankle joint(2 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alessandra Rezende Martinelli

PhD student

University of Sao Paulo

研究点 (1)

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