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Clinical Trials/NCT01912794
NCT01912794
Unknown
Not Applicable

Postural Responses to External Perturbation in Post-Stroke: Sensorimotor Integration and Rehabilitation

University of Sao Paulo1 site in 1 country24 target enrollmentAugust 2013
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
University of Sao Paulo
Enrollment
24
Locations
1
Primary Endpoint
Displacement amplitude of the CP to the anterior-posterior and medial-lateral
Last Updated
12 years ago

Overview

Brief Summary

To maintain stable body balance in daily activities, the ability to respond to external perturbations is an essential factor. Such capacity is limited in pathological conditions, such as in stroke, in which postural control is impaired due to lesions to the central nervous system. Impairment to postural control increases body sway during upright posture and leads to augmented frequency of falls. In this sense, the identification of mechanisms involved in body balance disorders after stroke is particularly important in situations of postural perturbation. The purpose of this project is to evaluate reactive postural responses to unpredictable external perturbations, analyzing postural dysfunctions caused by lesion to different brain areas as a result of stroke, and test principles of dynamic body balance rehabilitation.

Registry
clinicaltrials.gov
Start Date
August 2013
End Date
October 2014
Last Updated
12 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alessandra Rezende Martinelli

PhD student

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • Inclusion criteria are as follows. Healthy participants: absence of detectable neurological or physical malfunction which might affect postural control, no use of drugs affecting body balance and preserved mental capacity. Stroke patients: capacity to sustain independently orthostatic posture for at least 5 min. and preserved mental capacity.

Exclusion Criteria

  • Exclusion Criteria are: no orthopedic malfunction, no clinical instability associated with systemic disease, no use of drugs affecting body balance and presence of "pusher syndrome".

Outcomes

Primary Outcomes

Displacement amplitude of the CP to the anterior-posterior and medial-lateral

Time Frame: 2 months

This outcome measure quantified by the difference between the maximum values of the anterior-posterior and medial-lateral after the start of trial and average position in the axis anteroposterior and mediolateral, respectively, in the 200 ms prior to the onset of the trial.

Secondary Outcomes

  • Coordination between the hip and ankle joint(2 months)

Study Sites (1)

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