Fertility Preservation in Transgender Persons: A Retrospective Look

Completed

• Conditions: Fertility Preservation in Transgender Persons

• Registration Number: NCT05120245
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Patients in this study will be asked how they feel about the decision to freeze gametes, using a validated questionnaire. In addition, a number of questions with free text fields will be included in the questionnaire to write down any reasons for their satisfaction or regret. In a second part, the intention to use the frozen material will be assessed. We focus on techniques with real perspectives (e.g. cryopreservation of oocytes and sperm cells) and not on techniques that are more experimental for later use (cryopreservation of ovarian and testicular tissue).

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-08
• Study First Submitted: 2021-09-15
• Study First Submitted QC: 2021-11-02
• Study First Posted: 2021-11-15
• Primary Completion: 2023-06-30
• Study Completion: 2023-06-30
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-12
• Last Update Posted: 2023-07-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Dutch speaking
• Sperm or oocyte preservation between june 2015 and june 2020. Survey in 2021

Exclusion Criteria

• Ovarian and testicular tissue cryopreservation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Satisfaction/ regret about the decision	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Survey on the reasons for satisfaction/ regret regarding the decision to freeze egg cells or sperm cells prior to gender-confirming hormonal or surgical treatment in the context of transition
Intention	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Examination of the intention to use the frozen egg cells or sperm cells to fulfil a desire to have children
Transgender people's retrospective view of the decision	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Study of transgender persons' retrospective evaluation of the decision to freeze egg or sperm cells prior to gender-confirming hormonal or surgical treatment in transition

Trial Locations

Locations (1)

Ghent University hospital; 🇧🇪 Ghent, Belgium