Investigating and comparing the therapeutic outcomes of two regimens of cholestin therapy through a bronchoscope versus standard treatment in patients with lung infectio

Phase 3

Recruiting

• Conditions: Ventilator Associated Pneumonia.; Ventilator associated pneumonia; J95.851

• Registration Number: IRCT20120527009886N3
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients with ventilator-associated pneumonia
Age between 18 and 75 years
Patients who developed pulmonary infection with gram-negative bacilli resistant to several antibiotic drugs after 48 hours of intubation.

Exclusion Criteria

Age older than 75 or younger than 18 years
Patients with adult respiratory distress syndrome (ARDS) according to the Berlin criteria
P/F ratio less than 100
Septic shock requires a dose of norepinephrine with a dose greater than 0.25 Mcg/KG/MIN
Patients with infection with other microorganisms

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality rate. Timepoint: After the start of treatment until the discharge or death of the patient. Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
The number of days hospitalized in the intensive care unit. Timepoint: After initiation of treatment until discharge or death from the intensive care unit. Method of measurement: Questionnaire.