An observational study for distribution of pattern identification in Parkinson’s disease
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0008677
- Lead Sponsor
- Kyung Hee University Oriental Medicine Hospital at Gangdong
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Patients with Parkinson disease
(1)Adult patients aged =19 years
(2)Diagnosis of idiopathic PD based on UK Parkinson’s Diseases Society Brain Bank criteria
(3)Hoehn and Yahr Scale stage 1–4
(4)Provide voluntary written informed consent to participate in this clinical study
Patient with Parkinson's disease
(1)Parkinson-plus syndromes (i.e., multisystem atrophy, progressive supranuclear palsy, corticobasal degeneration, dementia with Lewy bodies)
(2)History of neuropsychiatric disorder unrelated to PD
(3)Moderate or higher cognitive impairment that will interfere with the evaluation
(4) History of drug or alcohol abuse
(5) History of acute severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage), heart disease (myocardial infarction, heart failure, etc.), or malignant tumor within 6 months before screening, and receiving active treatment
(6) Inappropriate for enrollment due to other reasons as determined by the investigator
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pattern identification questionnaire ;Measurement of pulse and tongue;Unified Parkinson’s Disease Rating Scale (UPDRS) II, III;Gait analysis;Euro-Quality of Life-5 Dimension ;Hoehn & Yahr
- Secondary Outcome Measures
Name Time Method Analysis of changes in blood a-synuclein and cytokines (TNF-a, IFN-?, IL-1 ß, IL-8, etc.);Analysis of microbial diversity and dominant microbial community and diversity