NCT02804555已完成不适用
Effects of Intraoperative Oxygen Therapy on Oxygenation and Reactive Oxygen Species Levels of Newborns Born Via Elective Cesarian Section
Szeged University2 个研究点 分布在 1 个国家目标入组 107 人开始时间: 2013年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 107
- 试验地点
- 2
- 主要终点
- Hyperoxia Newborns
研究概览
简要总结
In this study the investigators examine the effects of intraoperative oxygen administration to the mother on certain enzyme functions of the newborn. With this object blood samples are taken from the newborn's umbilical chord - which is otherwise a routine practice at the investigators clinic - and the mother's radial artery in parallel with umbilical clamping and cutting for blood gas and reactive oxygen species analyses. Samples are analyzed locally in a properly equipped laboratory.
详细描述
Whole-blood superoxide and hydrogen peroxide production was measured from the newborn's umbilical chord.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective cesarean section.
- •Signed informed consent form.
排除标准
- •Subject meets the definition of a vulnerable subject as defined in International Organization for Standardization 14155:2011.
结局指标
主要结局
Hyperoxia Newborns
时间窗: through study completion up to two years
We measured umbilical vein blood gas parameters.
次要结局
- Maternal hyperoxia(through study completion up to two years)
- Alterations in newborns' enzyme functions due to maternal hyperoxia(through study completion up to two years)
研究者
Domonkos Trásy
clinician
Szeged University
研究点 (2)
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