Discrete Choice Experiments for HIV Prevention in Atlanta Adolescents- Atlanta
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Acceptability/Usability
研究概览
简要总结
This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults (AYAs) and adult supports.
详细描述
HIV pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV infections, reducing the risk by over 90%. However, adherence among AYAs remains suboptimal, with only 34% maintaining adherence at 48 weeks. Studies suggest that adult support can improve adherence in pediatric HIV treatment, but this approach has not been systematically evaluated for PrEP use in AYAs. Prior research indicates that Black AYAs and their families are open to incorporating adult support for PrEP adherence. Given the success of mobile health (mHealth) interventions in promoting sexual health, this study aims to enhance the HealthMPowerment (HMP) app-an existing mHealth platform designed for HIV prevention-to facilitate dyadic communication between Black AYAs and trusted adult support persons.
The study addresses the high rates of HIV among Black adolescents and young adults (AYAs) in metro Atlanta, Georgia, where AYAs (ages 13-24) account for 21% of new HIV diagnoses, with Black gay and bisexual males, transgender individuals, and heterosexual young women being disproportionately affected. Nearly half of new infections occur in rural areas. The U.S. Department of Health and Human Services Ending the HIV Epidemic initiative prioritizes four counties in metro Atlanta (Cobb, DeKalb, Fulton, and Gwinnett) as geographic hotspots, emphasizing the need for patient-centered interventions to reduce HIV incidence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 21 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •African Americans
- •Living in metropolitan Atlanta counties- Cobb, DeKalb, Fulton, Gwinnett
- •Have a PrEP indication (e.g., sex with a partner living with HIV, condomless sex, sex with multiple partners, engagement in transactional sex, or at least one sexually transmitted infection in the past 6 months)
- •Support Person:
- •self-reported provision of instrumental, informational, or emotional support for a Black AYA 14-21 years old
排除标准
- •HIV positive Inability to provide consent
研究组 & 干预措施
AYA group
All enrolled participants (AYAs and support persons) will receive a demonstration of the app, including all of its features. All participants will use the app for 6 months. Each dyad of participants will be instructed to use the app to communicate with each other and AYAs will be instructed to use the app to keep track of their PrEP.
Data from the medication tracker will be collected at 1-,
3-, and 6-months
干预措施: Health MPowerment App (Behavioral)
结局指标
主要结局
Acceptability/Usability
时间窗: 1 month, 3 months, and 6 months
The study evaluates an app's impact through post-intervention interviews, focusing on user experience, ethical concerns, and future usage intentions. It explores burden, satisfaction, attitudes, and how the app influences communication and adherence. Sekhon's Theoretical Framework of Acceptability will be utilized to measure this outcome.
Feasibility: Communication
时间窗: 1 month, 3 months, and 6 months
Communication between adolescents and young adults (AYA) and support person (i.e., Experience using chat features; Experience using forums). A modified version of Structured Assessment of FEasibility (SAFE) will be utilized to measure this outcome.
次要结局
- Medication Adherence Tracker(1 month, 3 months, and 6 months)
- Data Usage(1 month, 3 months, and 6 months)
研究者
Samantha Hill
Assistant Professor
Emory University