The role of steroids in infection-related glomerulonephritis

Not Applicable

Completed

• Conditions: Infection-related glomerulonephritis; Urological and Genital Diseases

• Registration Number: ISRCTN13723530
• Lead Sponsor: Madras Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-11-30
• Study Start: 2021-02-28
• Last Update Posted: 8 March 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

1. Patients older than 18 years who provide written informed consent
2. Fulfilment of 3/5 of the Nasr et al. criteria for infection-related glomerulonephritis
3. Serum creatinine >1.5 mg/dl at time of randomisation

Exclusion Criteria

1. More than 21 days elapsed since presentation
2. Presence of a contraindication for steroids
3. Seropositivity for HIV, hepatitis B, or hepatitis C
4. Hypocomplementaemia at 3 months
5. IgA-dominant infection-related glomerulonephritis
6. Crescents involving >50% of the sampled glomeruli
7. Diabetic nephropathy class III or IV
8. Interstitial fibrosis and tubular atrophy >40%

Study & Design

• Study Type: Interventional
• Study Design: Not specified