ISRCTN13723530
Completed
未知
A randomized controlled trial of corticosteroids in infection-related glomerulonephritis
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Madras Medical College
- Enrollment
- 86
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients older than 18 years who provide written informed consent
- •2\. Fulfilment of 3/5 of the Nasr et al. criteria for infection\-related glomerulonephritis
- •3\. Serum creatinine \>1\.5 mg/dl at time of randomisation
Exclusion Criteria
- •1\. More than 21 days elapsed since presentation
- •2\. Presence of a contraindication for steroids
- •3\. Seropositivity for HIV, hepatitis B, or hepatitis C
- •4\. Hypocomplementaemia at 3 months
- •5\. IgA\-dominant infection\-related glomerulonephritis
- •6\. Crescents involving \>50% of the sampled glomeruli
- •7\. Diabetic nephropathy class III or IV
- •8\. Interstitial fibrosis and tubular atrophy \>40%
Outcomes
Primary Outcomes
Not specified
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