Exercise during hemodialysis increases the removal of accumulated substances in the body

Not Applicable

• Conditions: Hemodialysis; E02.870.300

• Registration Number: RBR-97vpjx
• Lead Sponsor: niversidade Católica de Pelotas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-09-17
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with chronic kidney disease treated for hemodialysis for more than three months; aged 18 or over; in the use of arteriovenous fistula, as access for hemodialysis; with clinical and hemodynamic stability, in the last month of dialysis therapy those who presented hypotensive episodes in less than 15% of the sessions; able to perform the protocol of proposed physical exercises; agreed to participate in the study

Exclusion Criteria

Patients with cardiac events in the last three months; with current diagnosis of infection or neoplasias; history of deep vein thrombosis in the last three months; with systolic blood pressure equal to or greater than 180 at rest; diastolic blood pressure equal to or greater than 105 at rest; resting heart rate above 120 beats per minute; cognitive alterations that make it impossible to understand the instructions of the exercises; pregnant women

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Equilibrated and single pool Kt/V-urea, calculated by Daugirdas second generation equation,to assess adequacy of hemodialysis(HD).<br><br>;Rate of urea reduction, measured as percentage before, immediately after the HD and 30 minutes after each session HD,to assess adequacy of HD.;Serum rebound of urea,in percentage,calculated by the equation [(solute30 – solutef)/solutef] * 100, where solute30 is the plasma solute concentration 30 minutes after HD session and solutef is the plasma solute concentration immediately after the HD session,to assess adequacy of HD.<br><br><br>

Secondary Outcome Measures

Name	Time	Method
Total mass of dialysate urea, measured in grams, in continuous and fractionated samples of dialysate,to assess adequacy of HD.;Total mass of dialysate phosphorus, measured in grams, in continuous and fractionated samples of dialysate, to assess adequacy of HD.;Serum rebound of phosphorus, in percetage, calculated by the equation [(solute30 – solutef)/solutef] * 100, where solute30 is the plasma solute concentration 30 minutes after HD session and solutef is the plasma solute concentration immediately after the HD session,to assess adequacy of HD.