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Treatment of Spastic Equinovarus Foot After Stroke

Not Applicable
Completed
Conditions
Spastic Equinovarus
Registration Number
NCT00199589
Lead Sponsor
University Hospital, Limoges
Brief Summary

This study evaluates treatment for spastic foot after stroke using ankle foot orthosis with or without selective injection of BTA (Botox).

Detailed Description

This prospective, multicentric open trial evaluates the efficacy of a combined treatment for spastic foot after stroke using ankle foot orthosis with or without selective injection of BTA (Botox) into the tibialis anterior and/or posterior and/or the long toe flexor, and/or medial and lateral gastrocnemius, and/or soleus muscles \[300 BTA U per injection (Botox - Allergan), diluted with saline to a concentration of 5U/0,1 mL, with electromyography guided injection\]. The patients are followed for one year after treatment.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
46
Inclusion Criteria
  • Stroke patient with equinovarus foot due to severe lower limb extensor spasticity with impaired foot contact during walking
  • Ability to walk for at least 10 meters with or without aid
  • Stroke interval < 12 months
  • Age > 18 years old
  • Weight > 30 kg and < 100 kg
  • Written informed consent
Exclusion Criteria
  • Stroke interval > 12 months
  • Age < 18 years old
  • Pregnancy
  • Neuromuscular disease
  • Previous treatment with BTA
  • Fixed contractures impairing mobility
  • Mini-Mental Status Examination < 25
  • Aminosides treatment.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Plantar contact during walking
Secondary Outcome Measures
NameTimeMethod
Gait velocity
Barthel index
MIF
Autosatisfaction by EVA
Asworth scale
Ankle range of motion

Trial Locations

Locations (2)

Département de Médecine Physique et de Réadaptation

🇫🇷

Bordeaux, France

Département de Médecine Physique et de Réadaptation, CHU Limoges

🇫🇷

Limoges, France

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