MedPath

ACL Reconstruction With a New Generation of LARS Artificial Ligament

Not Applicable
Active, not recruiting
Conditions
ACL Injury
Registration Number
NCT06571955
Lead Sponsor
MOVMEDIX
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Active, not recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion Criteria:<br><br> - Subject is able to verbally confirm understanding of risks, benefits and treatment<br> alternatives of receiving the grafted ligaments<br><br> - Subject provides written informed consent approved by the EC prior to any clinical<br> investigation related procedure<br><br> - Subject must agree to undergo all clinical investigation plan - required clinical<br> follow-up visits<br><br> - Subject must agree not to participate in any other clinical investigation for a<br> period of 1 year following the procedure<br><br> - Male and female subjects over 40 years old.<br><br> - MRI positive for full acute ACL injury<br><br> - Arthrometric evaluation (KT1000) with a side-to-side difference greater than 3 mm<br><br> - Symptomatic subjects with no previous knee injury<br><br> - Subjects without concomitant pathologies (fracture, infections, immunodepression,<br> HIV, HCV) that could influence the outcome of the study or prevent the subject from<br> following the post-operative follow-up program as per protocol<br><br> - I and II degree chondral lesions<br><br>Exclusion Criteria:<br><br> - Subjects under 40 years old<br><br> - III and IV degree chondral lesions<br><br> - Associated ligament injuries<br><br> - Meniscus suture (e.g Handle bucket meniscal tears) that compromise the<br> rehabilitation program<br><br> - History for sepsis<br><br> - Subjects with concomitant pathologies (fracture, infections, immunodepression, HIV,<br> HCV,) that could influence the outcome of the study or prevent the subject from<br> following the post-operative follow-up program as per protocol<br><br> - Previous knee injuries<br><br> - Septic arthritis<br><br> - Infected tissues<br><br> - Pregnancy<br><br> - Overweighed, Obese subject (>100kg)<br><br> - History of metabolic bone disease<br><br> - Inflammatory joint disease<br><br> - Known neoplastic disease<br><br> - Medical treatment (e.g steroid)<br><br> - HIV positive subject<br><br> - Hepatitis positive subject<br><br> - Allergy to Titanium, PET, Ugurol, Gentamicin, Polystyrene Sulfonate, other<br> medication

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of Serious Adverse Device Effect (SADE)
Secondary Outcome Measures
NameTimeMethod
Assessment of patients' opinion about their knee and associated problems;Assessment of patients' pain intensity;Assessment of overall knee function;Assessment of posterior-anterior knee laxity;Assessment of knee flexors-extensors strength;Assessment of stabilometry
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