NL-OMON31923已完成不适用
Acute and chronic inflammatory responses induced by smoking in individuals being susceptible and non-susceptible for development of COPD: from specific disease phenotyping towards novel made therapy (study 1). - Acute smoking in COPD
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Age 18-75 years
- •Age, pack years, FEV1/FVC and FEV1% predicted must fit in one of the 5 groups of table 4.1
- •Able to stop smoking for 10 days and start smoking 3-4 cigarettes within 1 hour
- •Physically and mentally able to undergo the total study protocol
- •Written informed consent
排除标准
- •Participation in another study
- •Alpha-1-antitrypsin deficiency
- •Selected grade 1-3 co-morbidity listed in the ACE-27
- •Active pulmonary infection like tuberculosis, pneumonia, flue, tracheobronchitis
- •Active extra-pulmonary infection like hepatitis A-C, cystitis, gastro-enteritis etc
- •Pulmonary diseases like sarcoidosis, IPF, silicosis, hypersensitivity pneumonitis
- •Life threatening diseases like carcinoma, AIDS (including HIV+), acute leukaemia etc
- •Medication that may affect the results of the study: NSAID*s, immunosuppressive agents like prednisolon, metotrexate, azathioprine,Sintrom tablets
研究者
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