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Clinical Trials/NL-OMON38401
NL-OMON38401
Completed
Not Applicable

Microvascular flow and microvascular blood volume measurements in human skeletal muscle using contrast enhanced ultrasound (CEUS). - CEUS reproducibility study.

niversiteit Maastricht0 sites8 target enrollmentTBD
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Conditionsmicrovascular insulin resistanceobesity1001842410057166

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
microvascular insulin resistance
Sponsor
niversiteit Maastricht
Enrollment
8
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
October 7, 2013
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 18\-55 years
  • •2\. BMI \< 25 kg/m2 \*;\* \= most likely to have intact capillary recruitment in skeletal muscle (a parameter studied in this research protocol).

Exclusion Criteria

  • •1\. Cardiovascular disease (stroke, coronary artery disease, peripheral vascular disease, heart failure, cardiac shunts, heart valve replacement, pulmonary hypertension).
  • •2\. Pulmonary disease.
  • •3\. Diabetes mellitus (FPG \> 7\.8 mmol/L).
  • •4\. Smoking.
  • •5\. Hypertension (\>140/90 mmHg).
  • •6\. Alcohol use \> 4 U/day.
  • •7\. Use of medication (antihypertensive medication, statins, corticosteroids, NSAIDs, ciclosporin A, rifampicin).
  • •8\. Pregnancy or lactation.
  • •9\. Insufficient knowledge of the Dutch language.
  • •10\. Known allergic reaction to ultrasound contrast\-agent.

Outcomes

Primary Outcomes

Not specified

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