Impact of Belt Position on the Results of PEEP Titration by Electrical Impedance Tomography During Acute Respiratory Distress Syndrome
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 20
- Primary Endpoint
- Impact of the position of the electrode belt on the results of PEEP titration by EIT.
Study Overview
Brief Summary
ARDS is a frequent reason for hospitalization in intensive care. In order to improve its management, doctors seek to limit the mechanical ventilation-induced injuries (VILI) that can occur. PEEP is a parameter that plays a role in the appearance of VILI, and its adjustment can be optimized by EIT. The EIT is a non-invasive, non-irradiating, real-time monitoring device, today widely used for the optimization of ventilation in patients intubated for ARDS. The positioning of the EIT belt at different chest heights could influence the result of the PEEP titration.
Detailed Description
The aim of this study is to test the hypothesis that the position (2nd intercostal space or 5th intercostal space) of the EIT (Electrical Impedance Tomography) belt significantly influences the result of PEEP (Positive Expiratory Pressure) titration.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Occurrence of moderate to severe ARDS (PaO2/FiO2 ratio ≤ 200 mmHg) within 72 hours following intubation
- •Criteria for moderate to severe ARDS for less than 72 hours
- •Passive ventilation in controlled assisted ventilation (no spontaneous ventilation)
- •Consent of next of kin
Exclusion Criteria
- •Age < 18 years
- •Pneumothorax
- •Pacemaker or implantable defibrillator
- •Chest trauma in the last 3 months
- •Skin peeling (Burned, Lyell)
- •Intracranial hypertension
- •Uncontrolled shock (noradrenaline >5 mg/h)
- •Pregnant woman
- •Adult patient protected within the meaning of the law
- •Lack of social security
Arms & Interventions
PEEP titrations
Intervention: EIT (Device)
Outcomes
Primary Outcomes
Impact of the position of the electrode belt on the results of PEEP titration by EIT.
Time Frame: Day 0
Optimal PEEP determined by PEEP titration using the crossing point method.
Secondary Outcomes
- Discrepancy between compliance measured according to impedance and compliance measured according to exhaled volume(Day 0)
- Factors associated with a discordance between PEPEIT and PEPCRS(Day 0)
- Impact of the existence of intra-tidal recruitment on the discordance between PEPEIT and PEPCRS(Day 0)