跳至主要内容
临床试验/NCT03188900
NCT03188900
已完成
不适用

New Therapeutic Strategy Against Preeclampsia: Angiogenic Switch to Physiological State by Extracorporeal Removal of sFlt-1

Assistance Publique - Hôpitaux de Paris1 个研究点 分布在 1 个国家目标入组 236 人2017年6月12日
适应症Preeclampsia

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Preeclampsia
发起方
Assistance Publique - Hôpitaux de Paris
入组人数
236
试验地点
1
主要终点
ratio sFlt-1/PlGF
状态
已完成
最后更新
上个月

概览

简要总结

The aim of the study is to setup a collection of maternal plasma and serum from patients with preeclampsia and normal pregnancy for in vitro validation of new therapeutics based on extra-corporal removal of sFlt-1

详细描述

A collection of maternal plasma and serum from patients with preeclampsia (PE) and normal pregnancy (NP) : * Between 20WG and 23WG+6D : 20 patients with PE and 30 patients with NP * Between 24WG and 27WG+6D : 20 patients with PE and 30 patients with NP * Between 28WG and 31WG+6D : 20 patients with PE and 30 patients with NP * Between 32WG and 35WG+6D : 20 patients with PE and 30 patients with NP * Between 36WG and 40WG+6D : 20 patients with PE and 30 patients with NP

注册库
clinicaltrials.gov
开始日期
2017年6月12日
结束日期
2019年6月12日
最后更新
上个月
研究类型
Observational
性别
Female

研究者

入排标准

入选标准

  • Age from 18 to 50 years old
  • Singleton pregnancies between 20 and 41 weeks of gestation
  • Preeclampsia
  • Normal pregnancy

排除标准

  • Infectious disease: HIV, HBV or HCV
  • Multiple pregnancies
  • Opposition of the patient

结局指标

主要结局

ratio sFlt-1/PlGF

时间窗: Day 0

measurement of of sFlT-1 and PlGF

次要结局

  • Kinetics of these ratios sFlt-1/PlGF during pregnancy(until 5 month)

研究点 (1)

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