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Clinical Trials/NCT06512259
NCT06512259
Recruiting
N/A

A Retrospective Study To Evaluate The Safety And Effectiveness Of AlloMend® Acellular Dermal Matrix Used In Post Mastectomy Pre-Pectoral Breast Reconstruction And Followed For Up To 6-Months Post-Operatively.

AlloSource1 site in 1 country200 target enrollmentOctober 19, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Sponsor
AlloSource
Enrollment
200
Locations
1
Primary Endpoint
Descriptive Data Collection
Status
Recruiting
Last Updated
5 months ago

Overview

Brief Summary

This is a single-center, retrospective study which will be used to describe and evaluate the effectiveness of AlloMend® Acellular Dermal Matrix allograft for patients that have undergone Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy.

Detailed Description

AlloMend® Acellular Dermal Matrix is a sterile, ready to use, human-derived acellular dermal matrix (ADM) allograft that can be used in a number of reconstructive and other surgical procedures. It is made from donated human full-thickness skin. After the epidermal and hypodermal layers are removed, the tissue is treated by a proprietary cleansing process. AlloMend® is intended to be used in conjunction with a breast implant or tissue expander to stabilize implant position and minimize implant loss during post-single or double mastectomy, unilateral or bilateral pre-pectoral breast reconstruction in women 18 years of age or older. AlloMend® may be used in either one-stage (direct-to-implant) or two-stage (expander-to-implant) procedures.

Registry
clinicaltrials.gov
Start Date
October 19, 2023
End Date
December 31, 2026
Last Updated
5 months ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
AlloSource
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients must meet the following inclusion criteria to participate in this study:
  • Diagnosed by a physician and required a single or double mastectomy followed by Pre-Pectoral Breast Reconstruction surgery with the use of AlloMend® Acellular Dermal Matrix allograft;
  • Surgical intervention using AlloMend® Acellular Dermal Matrix allograft was used;
  • Has completed or will complete the anticipated clinically indicated follow-up visits at 2 weeks, 6 weeks, 3 months, and 6 months post-surgical intervention.

Exclusion Criteria

  • Patients must not meet any of the following criteria to be considered for this clinical trial:
  • Did not utilize AlloMend® Acellular Dermal Matrix allograft during pre-pectoral breast reconstruction
  • Did not have post-operative evaluations at the clinical site.

Outcomes

Primary Outcomes

Descriptive Data Collection

Time Frame: Up to 6- months post-operatively

The primary objective is to obtain descriptive data and surgical intervention and post operative surgical outcome data on AlloMend® Acellular Dermal Matrix allograft for patients that have undergone Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy.

Secondary Outcomes

  • Physical Function and Quality of Life(Up to 6- months post-operatively)

Study Sites (1)

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