Effects of physical exercise in the fadigue of the patient with heart and lung disease

Phase 1

Recruiting

• Conditions: Heart failure unspecified; Chronic obstructive pulmonary disease unspecified; I50.9; J44.9

• Registration Number: RBR-6649b2
• Lead Sponsor: niversidade Federal do Rio de Janeiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Group 1 (COPD): patients in this group will be selected based on the presence of the forced expiratory volume in the first second (FEV1) less than 60% of the predicted; with FEV1 / forced vital capacity (FVC) ratio less than 70%; who have symptoms of dyspnea on clinically stable efforts.
- Group 2 (CHF): patients must have documented heart failure in the last 6 months; with echocardiography showing an ejection fraction of less than 45% within the last 6 months; with classification between I-II of the disease according to New York Heart Association45; clinically stable and without episodes of hospitalization in the last month, non-smokers; non alcoholics; non-drug users who cause chemical dependency; who do not have COPD (FEV1 / FVC and FEV1 <70% of predicted) or unstable angina; or history of myocardial infarction in the last 6 months; or inability to exercise due to neuromuscular or musculoskeletal disorders; as well as other potential causes of fatigue.
- Group 3 (control): volunteers in this group will be selected because they are in good general health; in the absence of abnormalities in the cardiovascular, respiratory or musculoskeletal system and metabolic changes; sedentary (weak classification by the American Heart Association44)

Exclusion Criteria

Group 1: no absence of hypoxemia, ex-smokers; who do not have right heart failure; non alcoholics; non-drug users who cause chemical dependency; and who do not have an inability to perform the exercise due to neuromuscular or musculoskeletal disorders; as well as other potential causes of fatigue.
Group 2: non-smokers; non alcoholics; non-drug users who cause chemical dependency; who do not have COPD (FEV1 / FVC and FEV1 <70% of predicted) or unstable angina; or history of myocardial infarction in the last 6 months; or inability to exercise due to neuromuscular or musculoskeletal disorders; as well as other potential causes of fatigue.
Group 3: should not be smokers; drinkers; drug users who cause chemical dependency; without diabetes melitus, dyslipidemia and arterial hypertension; non-users of antihypertensive and cardioactive medications.
 

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluate the effect of a concurrent six-month physical training program using the cardiopulmonary tests to obtain the anaerobic threshold used to observe improvement in the functional capacity of patients with chronic cardiopulmonary diseases from the variation of at least 5% in the meters (consumption oxygen at anaerobic threshold) before and after intervention.

Secondary Outcome Measures

Name	Time	Method
Evaluate the effect of a concurrent six-month physical training program on vagal autonomic modulation, peripheral muscle strength and quality of life in patients with Chronic Cardiopulmonary Disease.<br><br>Evaluate the effect of a concurrent six-month physical training program using the maximum strength test to obtain the peak torque used to observe improvement in muscle strength in patients with chronic cardiopulmonary diseases from the variation of at least 5% in the meters (peak torque) before and after intervention.