A substudy of the PLAPCI trial comparing Phospholipase A2 release with tissue characteristics as determined by invasive ultrasound and infrared imaging of the heart arteries in patients with coronary artery disease undergoing coronary artery stenting.
Not Applicable
- Conditions
- Coronary artery diseaseCardiovascular - Coronary heart disease
- Registration Number
- ACTRN12611000869976
- Lead Sponsor
- Sir Charles Gairdner Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients undergoing elective percutaneous coronary intervention
age 18 to 85 years
Exclusion Criteria
Myocardial Ischaemic event <14 days prior to participation
Change in HMG Co-A reductase inhibitor (statin) in the last 30 days
Current acute or chronic inflammatory condition
Coronary vessels unsuitable for invasive imaging, including planned left main stenting
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To test the hypothesis that a greater percentage of coronary lipid core and the presence of thin cap fibro-atheroma as assessed by IVUS and OCT will correlate with greater relative PLA2 release during elective percutaneous coronary intervention and to identify which PLA2 assay shows the greatest correlation[prior to and after elective coronary intervention (approx 30mins apart)]
- Secondary Outcome Measures
Name Time Method nil[nil]