NCT02885584Unknown不适用
Conventional Mechanical Ventilation and High Frequency Percussive Ventilation: Comparison of Their Effects on Alveolar Recruitment and Distension by CT-scan in Early ARDS Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Percent of patients exhibiting under HFPV an increase of at least 15% of normally aerated end-expiratory lung volume
研究概览
简要总结
High frequency percussive ventilation (HFPV) is a high frequency ventilation mode in which high frequency pulses accumulate to generate a low frequency tidal volume at a controlled airway pressure. Previous studies have suggested a protective effect of HFPV on lung injury. The goal of our study is to compare, in early ARDS patients, the effects of conventional mechanical ventilation and of high frequency percussive ventilation on alveolar recruitment and distension evaluated by CT-scan
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient undergoing invasive ventilation for more than 24h
- •ARDS patient
排除标准
- •Pneumothorax drained or not
- •Patient undergoing extracorporel mechanical oxygenation
- •Patient who had a pneumonectomy partiel or total
结局指标
主要结局
Percent of patients exhibiting under HFPV an increase of at least 15% of normally aerated end-expiratory lung volume
时间窗: 4 hours
次要结局
未报告次要终点
研究者
研究点 (2)
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