Bronchial Obstruction in Dairy Farmers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,247
- 试验地点
- 1
- 主要终点
- Level of bronchial obstruction
研究概览
简要总结
Chronic Obstructive Pulmonary Disease (COPD) is a major public health problem and is expected to become the 3rd leading cause of death globally by 2020.
The main risk factor is tobacco. Tobacco poisoning is found in 80 to 90% of patients with COPD. However, non-smoking COPD is also described, with increasing prevalence figures, particularly related to occupational exposure, especially among farmers.
详细描述
A prospective screening study based on questionnaires and electronic mini-spirometry (Néo-6®) that includes a representative sample of dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany.
The dairy farmers had an occupational medicine appointment and, if they demonstrated at least one marker of possible bronchial obstruction (chronic cough, chronic bronchitis, dyspnoea, wheezing, spirometry), they were referred to a pulmonologist.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany
- •control: non farmer
排除标准
- •pigs or grain farmers
- •Pregnant women
- •oral corticosteroids or immunosuppressive drugs
结局指标
主要结局
Level of bronchial obstruction
时间窗: 3 years
Respiratory specific indices are extracted from a screening spirometry : Forced expiratory volume in one second (FEV1) Forced Vital Capacity (FVC) Bronchial obstruction is stated with a ratio FEV1 / FVC \< 0.8
次要结局
- Prevalence of occupational specific COPD in dairy farmers(3 years)