Effect of exercise on bone health for arm swelling after breast cancer

Phase 3

• Conditions: Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

• Registration Number: CTRI/2023/01/048813
• Lead Sponsor: Manipal Academy of Higher Education

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Breast cancer survivors with upper limb lymphedema after:

1. breast conservative surgery

2. modified radical mastectomy with axillary node dissection (levels I and II),

3. adjuvant chemotherapy and radiotherapy and

hormonal therapy

Exclusion Criteria

Participants unable to follow instructions

1. Musculoskeletal disorders (rheumatoid arthritis, fragility fractures involving upper limb, compartment syndrome) in which exercises cannot be performed.

2. Clinical evidence of impaired peripheral vascular circulation in affected limb with BCRL

3. Clinical evidence of acute cellulitis in affected limb with BCRL

4. End stage organ failure (renal, cardiac, hepatic)

5. Left ventricular ejection fraction < 25% with s/o congestive cardiac failure

6. Severe valvular heart disease

7. Participants with any acute illness

8. Stage IV breast cancer (ECOG score > 2)

9. Bilateral upper limb lymphedema

10. Participants receiving pharmacological treatment for osteoporosis and bone health

11. Participants on steroid therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified