Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins
Not Applicable
Completed
- Conditions
- Gastric Cancer
- Registration Number
- NCT02348229
- Lead Sponsor
- The First Hospital of Jilin University
- Brief Summary
The investigators designed a prospective randomized, controlled clinical trial then recruited 149 consecutive advanced gastric cancer patients. Further divided into a ERAS group (n=73) and a conventional pathway group (n=76). Surgical technique in both groups was same laparoscopic-assisted gastrectomy with D2 lymphadenectomy. Compared outcomes included clinical parameters and serum indicators.
- Detailed Description
Enhanced recovery after surgery combined with laparoscopic-assisted gastrectomy was successfully carried out in this study. Recovery parameters such as the length of time to return to normal diet,mean hospital stay (d) were recorded.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 149
Inclusion Criteria
- Age 18-75 years old
- Diagnosis confirmed by the endoscopic biopsy and total-body CT scan
- No history of the chronic renal disease ,chronic liver disease, cardiopulmonary dysfunction, ASA score≦3
- No neoadjuvant chemotherapy and radiotherapy
- No digestive obstruction and distant metastasis
Exclusion Criteria
- Conversion to open gastrectomy
- A large amount of bleeding leading(>500ml)
- Patients withdrew their consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Compartition of postoperative hospital stay up to 30 days after the operation
- Secondary Outcome Measures
Name Time Method Change from baseline in C-Reactive Protein( CRP) and visceral proteins level baseline and 5 days 1day before and 1-5days after operation