DIVERS-II: Treating depression in dialysis patients with a tailored eHealth cognitive based treatment: A cluster randomized controlled trial.

Recruiting

• Conditions: Depressie / Depression / Depressive disorderDialyse / Dialysis / Renal replacement therapyNierfalen / Eindstadium nierfalen / Kidney failure / End stage renal disease

• Registration Number: NL-OMON29658
• Lead Sponsor: OLVG Amsterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 206

Inclusion Criteria

• ≥18 years of age

• undergoing dialysis treatment for at least 90 days

Exclusion Criteria

• Suicidal thoughts (measurend using a short screening survey)

• Participation in other psychotherapeutic trials

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cluster randomized controlled trial of the intervention versus care as usual.<br /><br>The primary outcome is the depression score, measured using the Beck Depression Inventory (BDI). The difference between T0 and T1 (1-2 weeks after treatment) is the primary outcome for clinical effectiveness. Care as usual will be compared with the intervention group.<br>

Secondary Outcome Measures

Name	Time	Method
• BDI scores after 6, 12 and 18 months<br /><br>• Anxiety score, measured using the Beck Anxiety Inventory<br /><br>• Quality of life, measured using the SF-12<br /><br>• Inflammatory markers, cortisol and tryptophan to explore possible pathophysiological mechanisms<br /><br>• Explore the effect on morbidity (hospital admissions) and mortality