Long Term Oral and Dental Effects in Adolescents Who Were Treated for Cancer in Childhood
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cancer
- Sponsor
- Hadassah Medical Organization
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Oral abnormalities associated with cancer therapy.
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The investigators aim is to explore associations between specific types of cancer therapy, age at treatment and the presence of dental abnormalities in adolescence.
The study will help identify unique dental changes, malformations and or missing teeth that appear in adolescence as a secondary complication due to anticancer treatment (chemotherapy and or radiotherapy) given in childhood.
Materials and methods:
- Study Group: 200 patients, at least 12 years old, who were treated for Cancer at the age of 0-10 years old.
- The following data will be collected: Demographic information, Medical Status, Cancer therapy, Intraoral examination, Oral soft and hard tissue condition and radiographic examination.
Investigators
Eligibility Criteria
Inclusion Criteria
- •were treated for Cancer at the age of 0-10 years old
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Oral abnormalities associated with cancer therapy.
Time Frame: Two years
A medical survey will be filled out with the patient and his legal guardian. A full dental examination will gather all clinical and radiographic findings. The following measures will be noted: 1. Description of chemotherapy agents and duration 2. Radiotherapy continuation. 3. Radiotherapy dosage in Gray units. 4. Yes/No questions regarding previous dental trauma. 5. Yes/No questions regarding previous dental treatment. 6. Questions regarding oral hygiene. 7. Questions concerning oral habits. 8. Extra oral examination. 9. Intra oral clinical findings will be listed by tooth number. 10. Radiographic findings will be listed by tooth number.