Long Term Oral and Dental Effects in Adolescents Who Were Treated for Cancer in Childhood
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Oral abnormalities associated with cancer therapy.
研究概览
简要总结
The investigators aim is to explore associations between specific types of cancer therapy, age at treatment and the presence of dental abnormalities in adolescence.
The study will help identify unique dental changes, malformations and or missing teeth that appear in adolescence as a secondary complication due to anticancer treatment (chemotherapy and or radiotherapy) given in childhood.
Materials and methods:
- Study Group: 200 patients, at least 12 years old, who were treated for Cancer at the age of 0-10 years old.
- The following data will be collected: Demographic information, Medical Status, Cancer therapy, Intraoral examination, Oral soft and hard tissue condition and radiographic examination.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 32 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •were treated for Cancer at the age of 0-10 years old
排除标准
- 未提供
结局指标
主要结局
Oral abnormalities associated with cancer therapy.
时间窗: Two years
A medical survey will be filled out with the patient and his legal guardian. A full dental examination will gather all clinical and radiographic findings. The following measures will be noted: 1. Description of chemotherapy agents and duration 2. Radiotherapy continuation. 3. Radiotherapy dosage in Gray units. 4. Yes/No questions regarding previous dental trauma. 5. Yes/No questions regarding previous dental treatment. 6. Questions regarding oral hygiene. 7. Questions concerning oral habits. 8. Extra oral examination. 9. Intra oral clinical findings will be listed by tooth number. 10. Radiographic findings will be listed by tooth number.
次要结局
未报告次要终点