A Prospective Randomised Trial Comparing Three Interventions to Improve Treatment Adherence Among Patients With Arterial Hypertension or Diabetes in Rural Cameroon (TAHADIRA-trial 1)

Brief Summary

Detailed Description

Non communicable chronic diseases such as arterial hypertension (AH) and diabetes (DM) are a great burden for public health in Cameroon. However, outside the main cities access to appropriate diagnosis and treatment of these health-conditions is still very poor. The Swiss NGO "Fondation Coopération Afrique" started in 2007 a program to integrate chronic disease management with focus on AH and DM into the primary health care system of peripheral non-physician health facilities in a rural area of Central Cameroon. A first evaluation after one year revealed very low treatment adherence among the newly diagnosed patients as the main challenge. In order to improve patient's adherence we expose them randomly to one of three interventions: The first intervention consists in a written agreement on long-lasting therapy (treatment contract). Patients get information about the importance of a regular long term treatment and personal engagement to follow treatment and clinical controls regularly. The second intervention introduces in addition to the treatment contract a reminder system. In case of follow-up failure a community worker traces the patient to recall the visit at the health centre. The third intervention consists of the treatment contract combined with a financial incentive in form of one month free treatment after four months of regular follow-up. We allocated randomly one of the three interventions to each health center.

Primary Outcomes

Secondary Outcomes

• Percentage of missed control-visits(One patient year)
• Treatment response of diabetic patients (fasting blood glucose)(One patient year)
• Treatment response of patients with arterial hypertension (blood pressure)(One patient year)