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Study on OsseoSpeed™ TX Narrow Implants in the Lower Jaw in a Chinese Population

Not Applicable
Completed
Conditions
Partially Edentulous Jaw
Interventions
Device: OsseoSpeed™ TX
Registration Number
NCT01473355
Lead Sponsor
Dentsply Sirona Implants and Consumables
Brief Summary

The purpose of this study is to investigate the clinical efficacy of OsseoSpeed™ TX 3mm diameter implant in a Chinese population by evaluation of marginal bone level alteration, implant stability and implant survival in the posterior mandible up to 3 years after loading. Hypothesis: Early loading of the 3 mm implant is a safe and predictable procedure.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
45
Inclusion Criteria

Not provided

Exclusion Criteria
  1. Unlikely to be able to comply with study procedures, as judged by the investigator
  2. Uncontrolled pathologic processes in the oral cavity
  3. Known or suspected current malignancy
  4. History of radiation therapy in the head and neck region
  5. History of chemotherapy within 5 years prior to surgery
  6. Systemic or local disease or condition that could compromise post-operative healing and/or osseointegration, as deemed by the investigator
  7. Uncontrolled diabetes mellitus
  8. Corticosteroids or any other medication that could influence post-operative healing and/or osseointegration
  9. Smoking more than 10 cigarettes per day
  10. Present alcohol and/or drug abuse
  11. Involvement in the planning and conduct of the study (applies to both Astra Tech staff and staff at the study site)
  12. Previous enrollment in the present study
  13. Simultaneous participation in another clinical study, or participation in a clinical study during the last weeks prior to enrollment

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
OsseoSpeed™ TXOsseoSpeed™ TXOsseoSpeed™ TX narrow implants (diameter 3 mm) in lengths of 11-15 mm
Primary Outcome Measures
NameTimeMethod
Number of Survived ImplantsMeasured at the 3 year follow-up after implant loading.

Implant survival rate evaluated by clinically and radiographically counting the number of implants remaining in function

Secondary Outcome Measures
NameTimeMethod
Number of Stable ImplantsMeasured at the 3 year follow-up after implant loading.

Implant stability evaluated clinically/manually (recorded as stable yes/no).

Evaluation of the Periimplant Mucosa Condition - By Assessment of PPDMeasured at the 3 year follow-up after implant loading.

Condition of the periimplant mucosa by assessment of probing pocket depth (PPD).

Change in pocket depth expressed in millimeters at the 3-year follow-up visit, compared to values obtained at delivery of permanent restoration, i.e. loading (baseline).

Negative value = increased pocket depth.

Evaluation of the Periimplant Mucosa Condition - By Assessment of BoPMeasured at the 3 year follow-up after implant loading.

Condition of the periimplant mucosa by assessment of Bleeding on Probing (BoP). Presented as % of implants that show presence of bleeding on probing at time of the 3-year follow-up visit.

Presence of PlaqueMeasured at the 3 year follow-up after implant loading.

Occurence of plaque around the study implant. Presented as number of implants that show presence of plaque at time of the 3 years follow-up visit after implant loading.

Marginal Bone Level AlterationMeasured at the 3 year follow-up after implant loading.

Marginal bone level determined from radiographs and expressed as the distance from a reference point on the implant to the most coronal bone-to-implant contact on the mesial and distal aspect of the implant. Marginal bone level expressed in millimeters at the 3 year follow-up visit compared to values obtained at delivery of permanent restoration i.e. loading (baseline).

Trial Locations

Locations (3)

Sichuan University

🇨🇳

Chengdu, China

The First Affiliated Hospital, College of Medicine, Zhejiang University

🇨🇳

Hangzhou, China

School of Stomatology, JiLin University, Hospital of Stomatology

🇨🇳

Changchun, China

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