A Randomized Open Label, Parallel Group Study to Evaluate the Hemodynamic Effects of Cafedrine/Theodrenaline vs Noradrenaline in the Treatment of Intraoperative Arterial Hypotension in Adults after Induction of General Anesthesia. - HERO-trial

TEVA-ratiopharm GmbH Medical Affairs0 个研究点目标入组 223 人开始时间: 2022年4月1日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•undergoing elective vascular surgery
•require arterial cannulation
•require advanced hemodynamic monitoring prior to induction of general anesthesia
•require antihypotensive drug treatment due to arterial hypotension

•a. The patient has a known hypersensitivity to any components of the IMPs stated in this protocol;
•b. The patient has a known hypersensitivity to sodium metabisulfite;
•c. The patient has bronchial asthma with sulfite hypersensitivity;
•d. The patient has diagnosis of clinical relevant mitral stenosis;
•e. The patient has diagnosis of clinical relevant aortic stenosis;
•f. The patient has a diagnosis of hyperthyroidism;
•g. The patient has a diagnosis of pheochromocytoma;
•h. The patient is going to receive any cardiac sensitizing agent (e.g. cyclopropane or halothane) or is going to have deep hypoxia or hypercapnia concomitant to application of IMP;
•i. The patient has uncontrolled hypertension as co-morbidity;
•j. The patient has sepsis, septic shock, or systemic inflammatory response syndrome (SIRS)

发起方

TEVA-ratiopharm GmbH Medical Affairs