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A Clinical Study to Test the Use of Cetilistat tablet in over weight individuals

Phase 3
Conditions
Health Condition 1: E669- Obesity, unspecified
Registration Number
CTRI/2019/11/021919
Lead Sponsor
Hetero Labs Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Adult male or female patients aged of 18-65 years

2. The patient with body mass index (BMI) =30 kg/m2

3. Females of childbearing potential who are sexually active must agree to use barrier contraceptives

4. Clinical laboratory evaluations (including clinical chemistry, hematology, and complete urinalysis) within the reference range

Exclusion Criteria

1. Patients with known hypersensitivity to any of the components of the study drugs

2. Patients with significant weight loss in the 3 months prior to screening

3. Patients with history of any serious systemic disease

4. Changes in the dosing of antihyperlipidemic or anti-diabetic drugs within 4 weeks of randomization

5. Patients with bacterial infections requiring treatment with oral or injectable antibiotics, or significant viral or fungal infections, before 4 weeks of screening

6. Patients with history of anaphylaxis associated with medicinal products

7. History of drug or alcohol abuse within the past 2 years

8. Currently is participating in another investigational study or has participated in an investigational study within 90 days prior to randomization

9. Any other serious disease or condition at screening (or randomization) that would compromise patient safety

10. Patients with the current/past infections such as tuberculosis, hepatitis, herpes and/or patients with immune system disorders like HIV and SLE

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The absolute change in body weightTimepoint: Week 12
Secondary Outcome Measures
NameTimeMethod
Change in FPGTimepoint: Week 12;Change in LDLTimepoint: Week 12;Change in waist circumferenceTimepoint: Week 12;Incidence of gastrointestinal adverse eventsTimepoint: All Visits;Proportion of patients achieving 5% to 10% weight lossTimepoint: Week 12
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