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Pilot Evaluation of the Thriving Mamas Programme

Not Applicable
Completed
Conditions
Perinatal Mental Health
Interventions
Other: The Thriving Mamas programme
Other: Usual care
Registration Number
NCT06040359
Lead Sponsor
King's College London
Brief Summary

The goal of this pilot study is to evaluate the feasibility, appropriateness, and acceptability of a mental health prevention intervention among adolescents during pregnancy and the year after birth (perinatal period) in Kenya and Mozambique. The main questions it aims to answer are:

* Is the intervention feasible, acceptable, appropriate, and delivered/received with high fidelity, to adolescent girls, their friends/family members and service providers?

* Are the implementation strategies acceptable, appropriate, feasible to all relevant stakeholders?

* What impact does the intervention have on adolescent mothers' mental health?

* What impact does the intervention have on adolescent mothers' social, economic, and education outcomes?

Participants will:

* Participate in nine individual and group sessions focused on improving mental and perinatal health literacy and increasing life skills

* Receive standard perinatal care

Researchers will compare findings with girls receiving standard perinatal care only to see if the intervention has an impact on adolescents' mental health, social, economic and education outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
141
Inclusion Criteria
  • Mentor mothers: (A) aged 20 years or older; (B) female; (C) experience of pregnancy and/or parenting; and (D) live within the study site
  • Adolescent girls: (A) up to 28 weeks pregnant; and (B) aged 15-19 years
  • Friends/family members: (A) identified by an adolescent or young woman participating in the study; (B) participation agreed by other participating girls; and (C) aged 18 years or older
Exclusion Criteria
  • Mentor mothers will be excluded from participating if they are unable to attend training or deliver the intervention sessions
  • Adolescent girls will be excluded from the study if they are unable to provide informed consent or are unable to participate in the intervention, due to existing health conditions
  • Friends/family members will not be excluded so long as they meet inclusion criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Thriving Mama programmeThe Thriving Mamas programmeNine meetings delivered in either group (5 meetings), individual (1 meeting), or family group (2 meetings) formats over 10 weeks with an additional individual meeting 10-12 weeks postpartum by a trained mother in the community. Each meeting focuses on the girl's physical and mental health, taking care of a newborn, life skills, future-planning and social support and community-based services. Meetings will take place in a mixture of private settings in health facilities, community facilities, and participant homes. Adolescents will also receive usual perinatal care.
Usual perinatal careUsual careEach visit includes care that is appropriate to the overall condition and stage of pregnancy and should include four main categories of care: 1. Identification of pre-existing health conditions (e.g., check for weight and nutrition status, anemia, hypertension, syphilis, HIV status); 2. Early detection of complications arising during pregnancy (e.g., check for pre-eclampsia, gestational diabetes); 3. Health promotion and disease prevention (e.g., tetanus vaccine, prevention and treatment of malaria, nutrition counseling, micronutrient supplements, family planning counseling); and 4. Birth preparedness and complication planning (e.g., birth and emergency plan, breastfeeding counseling, antiretrovirals for HIV positive women and reducing mother-to- child transmission of HIV)
Primary Outcome Measures
NameTimeMethod
Intervention Feasibility10-12 weeks post-partum

Feasibility of Intervention Measure (FIM); Subjective report of feasibility of intervention; measures the extent to which a new treatment, or an innovation, can be successfully used or carried out within a given agency or setting. Minimum=5, Maximum=25; higher score is better

Intervention Acceptability10-12 weeks post-partum

Acceptability of Intervention Measure (AIM); Subjective report of acceptability of intervention; A 5-item scale that measures the perception among implementation stakeholders that a given treatment, service, practice, or innovation is agreeable, palatable, or satisfactory. Minimum=5, Maximum=25; higher score is better

Intervention Appropriateness10-12 weeks post-partum

Intervention Appropriateness Measure (IAM); Subjective report of appropriateness of intervention; A 5-item scale that measures the perceived fit, relevance, or compatibility of the innovation or evidence-based practice for a given practice setting, provider, or consumer, and/or perceived fit of the innovation to address a particular issue or problem. Minimum=5, Maximum=25; higher score is better

Intervention FidelityThrough intervention delivery, an average of 24 weeks

Enhancing Assessment of Common Therapeutic Factors (ENACT); subjective report of provider fidelity and perception of care; Minimum=0; Maximum=13; higher score is better

Secondary Outcome Measures
NameTimeMethod
Training AppropriatenessImmediately after provider training

Intervention Appropriateness Measure (IAM); Subjective report of appropriateness of intervention; A 5-item scale that measures the perceived fit, relevance, or compatibility of the innovation or evidence-based practice for a given practice setting, provider, or consumer, and/or perceived fit of the innovation to address a particular issue or problem. Minimum=5, Maximum=25; higher score is better

KnowledgeBaseline and immediately after provider training

Study-specific measure of mentor mothers' knowledge of issues regarding pregnancy, childbirth, caregiving, mental health, and referral pathways will be assessed using a study-specific quiz based upon the intervention manual; Minimum=0, Maximum=16; higher score is better

Training AcceptabilityImmediately after provider training

Acceptability of Intervention Measure (AIM); Subjective report of acceptability of intervention; A 5-item scale that measures the perception among implementation stakeholders that a given treatment, service, practice, or innovation is agreeable, palatable, or satisfactory. Minimum=5, Maximum=25; higher score is better

Recruitment ratepre-intervention

Proportion of adolescents providing consent to participate in the study

Cost of interventionthrough study completion, an average of 24 weeks

Total and average cost of the intervention per participant

Adolescent parenting competencythrough study completion, an average of 24 weeks

Parenting Sense of Competency Scale; 17-item scale to measure adolescents' perceived parenting abilities. Minimum=17, Maximum=102. Higher scores indicate greater perceived competence.

Change in adolescent pregnancy attitudesBaseline and immediately after provider training

Study-specific attitudes towards adolescent pregnancy survey; Minimum=4, Maximum=20; lower score is better

Change in mental health attitudesBaseline and immediately after provider training

Social Distance Scale (SDS); The SDS measures the acceptability of different degrees of social distance and, by inference, the attitude of the respondent to the person with the condition; Minimum=1, Maximum=96; higher score is better

Provider competencyImmediately after provider training

Study-specific single 10-point scale to assess provider ability to deliver the intervention; Minimum=0, Maximum=10; higher score is better

Referral uptake10-12 weeks post-partum

Proportion of adolescents attending referral appointments

Training FeasibilityImmediately after provider training

Feasibility of Intervention Measure (FIM); Subjective report of feasibility of intervention; measures the extent to which a new treatment, or an innovation, can be successfully used or carried out within a given agency or setting. Minimum=5, Maximum=25; higher score is better

Change in adolescent depressionthrough study completion, an average of 24 weeks

Patient Health Questionnaire (PHQ-9); Nine-item screening tool which assesses depression symptoms according to clinical criteria. Minimum=0, Maximum=27. A score ≥10 indicates moderate to severe depression.

Change in adolescent anxietythrough study completion, an average of 24 weeks

Generalised Anxiety Disorder scale (GAD-7); Seven-item screening tool which assesses anxiety symptoms according to clinical criteria. Minimum=0, Maximum=21. A score ≥10 indicates moderate to severe anxiety.

Change in adolescent social supportthrough study completion, an average of 24 weeks

Multidimensional Scale of Perceived Social Support (MSPSS); The MSPSS is a 12-item scale which measures social support from family, friends and significant others. Minimum=12, Maximum=84. Higher scores indicate greater social support.

Change in adolescent quality of lifethrough study completion, an average of 24 weeks

WHO Quality of Life brief version (WHOQOL-BREF); 26-item scale assesses a respondent's perceived quality of life across four domains: physical health; psychological; social relationships; and environment. Total minimum=25, Total maximum=125. Higher scores indicate greater quality of life in a particular domain.

Perinatal appointment attendancethrough study completion, an average of 24 weeks

Number of participants attending antenatal appointments

Change in infant vaccinationBaseline and 10-12 weeks post-partum

Number of participants intending to or having had their babies vaccinated

Change in breastfeedingBaseline and 10-12 weeks post-partum

Number of participants intendng to or are currently breastfeeding

Change in perception of interventionBaseline and 10-12 weeks post-partum

Study-specific five-item measure assessing knowledge gained, interest in intervention, and support recieved; Minimum=0; Maximum=5; higher score is better

Change in intended time to next pregnancyBaseline and 10-12 weeks post-partum

Study-specific health behaviours questionnaire to assess intended or actual contraceptive Nuimber of participants that want more children who intend to wait at least 15 months before next pregnancy

Change in contraceptive useBaseline and 10-12 weeks post-partum

Number of participants intending to or currently using contraceptives to delay pregnancy

Trial Locations

Locations (2)

Aga Khan University

🇰🇪

Nairobi, Kenya

Centro Internacional para Saude Reprodutiva Mocambique

🇲🇿

Maputo, Mozambique

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