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The Prognostic Role of Tricuspid Annular Plane Systolic Excursion in Critically Ill Patients With Septic Shock

Completed
Conditions
Septic Shock
Interventions
Radiation: tricuspid annular plane systolic excursion (TAPSE)
Registration Number
NCT06008067
Lead Sponsor
Alexandria University
Brief Summary

The aim of this study is to evaluate the possible prognostic performance of RV dysfunction, as assessed by TAPSE, in non-cardiac patients with septic shock.

Detailed Description

The objective is to investigate the prognostic performance of right ventricular dysfunction, as assessed by tricuspid annular plane systolic excursion (TAPSE), in non-cardiac patients with septic shock.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Adult patients (18 - 64 years old) with septic shock after admission according to 2016 consensus definition (Sepsis-3).
Exclusion Criteria
  • Pregnant females
  • Trauma
  • Documented coronary heart disease
  • History of myocardial infarction
  • Myocarditis
  • Thrombo-embolic pulmonary disease
  • Valvular heart disease
  • Corpulmonale
  • Arrhythmia
  • Known left ventricular ejection fraction < 40%
  • Poor echocardiographic window

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Non-survivorstricuspid annular plane systolic excursion (TAPSE)Patients who died at or before day 28.
Survivorstricuspid annular plane systolic excursion (TAPSE)Patients who survived after day 28.
Primary Outcome Measures
NameTimeMethod
28-day mortalityDay 28

Mortality rate after at day 28.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Faculty of Medicine, Alexandria University Hospitals

🇪🇬

Alexandria, Egypt

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