A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China

• Conditions: Delirium on Emergence; Analgesia; Separation

• Registration Number: NCT04217915
• Lead Sponsor: China Medical University, China

Brief Summary

In 2018, the severe medicine branch of the Chinese Medical Association and the American Society of severe medicine successively updated the pain and sedation guidelines for severe patients (PADIS guidelines). In addition to the update of the original evaluation and management of pain and sedation and delirium, the new guidelines also increased the monitoring and management of early activities and sleep quality for severe patients. Therefore, it is necessary for us to investigate the compliance of the new guidelines for analgesia, sedation and delirium management among the medical staff of critical care, so as to find out the existing problems in the management of analgesia, sedation and delirium in critical care patients, and find solutions to improve the overall quality level of our management of critical care patients

Detailed Description

The first part is to master the current situation of analgesia, sedation and delirium management of ICU patients in China. In order to understand the compliance of Chinese ICU doctors and nurses with the PADIS guidelines, a questionnaire survey was conducted with the participation of multiple centers in China, aiming at the doctors and nurses with different seniority in the critical medicine department. At the same time, the total number of critically ill patients, pain, agitation and delirium assessment tools and critical patients in 2018 were investigated The incidence of pain, agitation and delirium, the implementation of early activities, the monitoring and evaluation of sleep quality, and related interventions, including real-world clinical data such as drug treatment and non drug treatment.The second part focuses on the management of severe delirium in ICU in China. For the patients with delirium in the above survey, a further in-depth and detailed survey shall be conducted, covering the basic diseases of the patients, the occurrence time of delirium, the type of delirium, relevant risk factors, the diagnosis method of delirium, the duration of delirium, the prevention and treatment measures (including drug treatment and non drug treatment measures), and the prognosis of delirium patients .

Study Timeline

• Study First Submitted: 2019-12-30
• Study First Submitted QC: 2020-01-03
• Study First Posted: 2020-01-06
• Status Verified: 2021-07
• Last Update Submitted: 2021-07-07
• Study Start: 2021-07-12
• Last Update Posted: 2021-07-13
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• Age ≥ 18 years old;
• stay in ICU for more than 24 hours and have used analgesics and Sedatives.

Exclusion Criteria

• Before entering the ICU, they had mental illness and dementia;
• coma or deep sedation could not be evaluated;
• brain injury, stroke sequelae, epilepsy and other brain diseases;
• nerious audio-visual dysfunction and unable to communicate normally.
• Pregnant and lactating women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compliance of ICU medical staff with PADIS guidelines	2020.12	The assessment tool is a self-designed questionnaire based on the guidelines, which is mainly used to assess the compliance of medical staff with the guidelines in their daily work

Secondary Outcome Measures

Name	Time	Method
Incidence of delirium	2020.12	Incidence of delirium in Chinese ICU patients with analgesia and sedation during the study period

Trial Locations

Locations (1)

the first hospital of China Medical University; 🇨🇳 Shenyang, Liaoning, China