Comparison of the effects of aerobic exercises and conventional chest physiotherapy in cystic fibrosis

Not Applicable

Recruiting

Conditions: cystic fibrosis with pulmonary symptoms.
Cystic fibrosis with pulmonary manifestations
E84.0

Registration Number: IRCT20210505051181N5

Lead Sponsor: Iran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Confirmed diagnosis of cystic fibrosis based on positive sweat test or genetics test by a specialist doctor
Age 6 to 18 years

Exclusion Criteria

Active hemoptysis, pneumothorax, hemodynamic instability, severe hypoxia, acute airway infection and cognitive disorders
Having cardiac disease such as heart failure or arrhythmia, neurologic and orthopedic disorders, or chest trauma
History of fever, IV antibiotics or hospitalization in the last 1 month
Having severe uncontrolled gastroesophageal reflux
Severe lung disease (FEV1% < 30%)
Lung transplantation or in the awaiting list
Requirement of additional oxygen with exercise
Having uncontrolled diabetics
Improper patient cooperation during treatment sessions
Absence in 3 or more consecutive sessions

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Forced expiratory volume in 1st second (FEV1). Timepoint: Before starting physiotherapy interventions and after completing 18 treatment sessions for each group. Method of measurement: spirometer.;6 minutes walk test (6MWT). Timepoint: Before starting physiotherapy interventions and after completing 18 treatment sessions for each group. Method of measurement: tape measure and field test.

Secondary Outcome Measures

Name	Time	Method
Sputum culture. Timepoint: Before starting physiotherapy interventions and after completing 18 treatment sessions for each group. Method of measurement: Sterile container and laboratory culture kit.;Forced vital capacity (FVC). Timepoint: Before starting physiotherapy interventions and after completing 18 treatment sessions for each group. Method of measurement: spirometer.;Quality of life. Timepoint: Before starting physiotherapy interventions and after completing 18 treatment sessions for each group. Method of measurement: cystic fibrosis questionnaire - revised (CFQ-R).