Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age - the Clinical Relevance of Newly Discovered Viruses
试验速览
- 阶段
- 不适用
- 入组人数
- 1,260
- 试验地点
- 3
- 主要终点
- To describe the clinical picture of a viral respiratory and/or gastrointestinal infection associated with a specific viral pathogen
研究概览
简要总结
With the use of molecular methods new viruses have been detected in respiratory and gastrointestinal tracts of both patients and asymptomatic subjects in recent years. The clinical importance of these viruses has not been adequately studied.
The aim of this study is to use molecular methods to detect viruses in upper respiratory tract and gastrointestinal tract of children with acute bronchiolitis, acute gastroenteritis and febrile convulsions and to try to correlate the severity of clinical picture with the amount of viruses present in clinical samples. The investigators will also try to detect the increase in specific antibodies in paired sera.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •presence of
- •acute bronchiolitis
- •acute gastroenteritis
- •febrile convulsion requiring hospital admission
排除标准
- 未提供
结局指标
主要结局
To describe the clinical picture of a viral respiratory and/or gastrointestinal infection associated with a specific viral pathogen
时间窗: In a 14-day period
次要结局
- To correlate the severity of clinical picture with the quantity of virus in clinical samples(In a 14-day period)