NCT00424580已完成不适用
Airway Responses to Montelukast and Desloratadine.
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Late asthmatic response (maximum percent decrease in FEV1)
研究概览
简要总结
Montelukast (for asthma) and desloratadine (for allergies) are effective therapy for their current uses. Part of what happens when your allergies trigger your asthma should be prevented by either of these drugs. This project is being conducted to determine if these drugs are effective, either alone or in combination, on controlling asthma that is triggered by allergies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •baseline FEV1 > or = 65% predicted
- •positive methacholine challenge (i.e. methacholine PC20 < or = 16mg/ml
- •positive allergen challenge
排除标准
- •negative skin prick test
- •lung condition/disease other than asthma
- •currently use montelukast and/or desloratadine
结局指标
主要结局
Late asthmatic response (maximum percent decrease in FEV1)
次要结局
- Early asthmatic response (maximum percent decrease in FEV1
- Changes in sputum cell/mediator content
- Changes in airway hyperresponsiveness (methacholine PC20)
研究者
研究点 (2)
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