NCT00002295已完成不适用
A Double-Blind Placebo-Controlled Study to Investigate the Action of Isoprinosine (Inosiplex) in Patients With Severe Acquired Immunodeficiency Syndrome
Newport Pharmaceuticals International2 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 2
研究概览
简要总结
To evaluate the effect of Isoprinosine in patients diagnosed as having AIDS relative to:
Laboratory (immunologic defects):
- Comparison of total helper and suppressor T-cell numbers among the groups.
- Comparison of changes in natural killer cell activity.
- Comparison of other laboratory findings among the groups.
Clinical changes:
- Comparison of the frequency of opportunistic infections among the groups.
- Comparison of the frequency of the development of AIDS-related malignancies.
- Comparison of other clinical manifestations relative to severity and time of onset.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Exclusion Criteria
- •Co-existing Condition:
- •Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction, and severe gastric ulcer are excluded.
- •Concurrent Medication:
- •Steroids.
- •Cytotoxic immunosuppressive agents.
- •Radiotherapy.
- •The following are excluded:
- •Critically ill patients.
- •Patients receiving steroids, cytotoxic immunosuppressive agents, radiotherapy.
- •Patients who have received any other immunotherapy.
- •Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction, and severe gastric ulcer.
- •Prior Medication:
- •Any other immunotherapy.
- •Patients with severe AIDS and specified laboratory immunologic defects.
排除标准
- 未提供
研究者
研究点 (2)
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