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临床试验/EUCTR2008-001738-29-GB
EUCTR2008-001738-29-GB进行中(未招募)1 期

Renin angiotensin Aldosterone (RAAS) axis, endothelial function and hypertension: diagnostic strategies and therapeutic role of potassium supplementation

Belfast Health and Social Care Trust0 个研究点目标入组 40 人开始时间: 2008年8月21日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

入选标准

  • 50–70 years old with a 10-20% cardiovascular disease risk , (BMI) < 30 kg/m2, a (fasting plasma) glucose less than 7mmol/l, plasma potassium less than 5mmol/l, normal renal function (eGFR > 60), a treated BP < 140/85 mmHg and a 24hour urinary sodium >100mmol/24hrs.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Exclusion - history of renal or cardio vascular disease,fasting glucose greater than or equal to 7mmol/l, interfering medications with the RAAS axis (namely diuretics, ACE inhibitors, angiotensin receptor blockers, aldosterone antagonists, calcium blockers or beta-blockers). Patients on HRT will also be excluded. Given the age of inclusion, pregnancy is unlikely however pregnant or lactating women will also be excluded.

研究者

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