EUCTR2008-001738-29-GB进行中(未招募)1 期
Renin angiotensin Aldosterone (RAAS) axis, endothelial function and hypertension: diagnostic strategies and therapeutic role of potassium supplementation
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •50–70 years old with a 10-20% cardiovascular disease risk , (BMI) < 30 kg/m2, a (fasting plasma) glucose less than 7mmol/l, plasma potassium less than 5mmol/l, normal renal function (eGFR > 60), a treated BP < 140/85 mmHg and a 24hour urinary sodium >100mmol/24hrs.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Exclusion - history of renal or cardio vascular disease,fasting glucose greater than or equal to 7mmol/l, interfering medications with the RAAS axis (namely diuretics, ACE inhibitors, angiotensin receptor blockers, aldosterone antagonists, calcium blockers or beta-blockers). Patients on HRT will also be excluded. Given the age of inclusion, pregnancy is unlikely however pregnant or lactating women will also be excluded.
研究者
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