NCT04549012Unknown早期 1 期
Tranexamic Acid Plus Oxytocin Versus Oxtocin Only in Reducing Blood Loss After Cesarean Section
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 130
- 主要终点
- amount of blood loss
研究概览
简要总结
Comparing betweeen tranexamic acid plus oxytocin and oxytocin alone in their efficacy in reducing blood loss following CS
详细描述
tranexamic acid plus oxytocin versus oxytocin only in reducing blood loss following CS
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
盲法说明
women will be given serial number ,randomization will be done through a computer generated system
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age : 20-40 year
- •2- Gestational age is between 37-41weeks
- •3- Delivery by uncomplicated elective CS
排除标准
- •1- Risk factors for uterine atony such as polyhydramnios or fetal macrosomia. 2- Grandmultiparity 3- Past history of postpartum hemorrhage either atonic or traumatic 4- Previous history of retained placenta 5- Pre-eclampsia or gestational hypertension/ Maternal DM 6- Abnormal placentation 7- Contraindications to the use of tranexamic acid 8- Hypersensitivity to tranexamic acid. 9- Women receiving anticoagulant therapy. 10- having underlying disease (heart, liver, kidney, pulmonary, etc.),
研究组 & 干预措施
group A
Active Comparator
will receive oxytocin
干预措施: Oxytocin (Drug)
group B
Active Comparator
will receive tranexamic acid plus oxytocin
干预措施: Tranexamic acid (Drug)
结局指标
主要结局
amount of blood loss
时间窗: baseline
comparison between effect of oxytocin alone and tranexamic acid and oxytocin in reducing blood loss after CS
次要结局
- maternal and neonatal complication(baseline)
研究者
Noha Mahmoud Abu Shata
egypt
Ain Shams University
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