NCT01915641CompletedNot Applicable
CPAP Improves the Walking Capacity in Patients With COPD and OSA
Chang Gung Memorial Hospital1 site in 1 country60 target enrollmentStarted: April 1, 2013Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- exercise capacity (walking distance (meter), measured by incremental shuttle walking test)
Study Overview
Brief Summary
We have reported that CPAP treatment improved the walking capacity of overlap syndrome patients.
However, the previous study was not randomized, double blinded study. Therefore, we design a prospective, randomized, double blinded, controlled, cross-over trial to confirm this finding.
Detailed Description
inclusion criteria :
- COPD : FEV1/FVC < 70%, no response to bronchodilator (FEV1 change <12% and <200ml)
- OSA : AHI > 15/h, obstructive type predominant
exclusion criteria :
- any malignancy
- pregnancy
- claustrophobia
- age<18
primary outcome : exercise capacity (walking distance (meter), measured by incremental shuttle walking test)
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •FEV1/FVC < 70%, no response to bronchodilator (FEV1 change <12% and <200ml)
- •OSA : AHI > 15/h, obstructive type predominant
Exclusion Criteria
- •any malignancy
- •pregnancy
- •claustrophobia
Outcomes
Primary Outcomes
exercise capacity (walking distance (meter), measured by incremental shuttle walking test)
Time Frame: CPAP treatment for 1 month
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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