EUCTR2011-002566-21-IT进行中（未招募）不适用
A Phase 2 Open-label Study of MEDI-551 and Bendamustine vs Rituximab and Bendamustine in Adults With Relapsed or Refractory C
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 156
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Histologically confirmed aggressive B-cell Chromic Lymphocytic Leukemia( CLL) according to the National Cancer Institute criteria •Adequate hematological function
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 130
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 26
排除标准
- •Any chemotherapy, radiotherapy, immunotherapy, biologic, investigational or hormonal therapy for treatment of lymphoma within 42 days prior to treatment • Exposure to Bendamustine within 180 days before study enrollment • Any active secondary malignancy • Prior autologous or allogeneic stem cell transplantation SCT • Clinically significant abnormality on ECG • History of other invasive malignancy within 5 years except for localized/in situ, carcinomas such as cervical carcinoma in situ or basal/squamous skin cancer. • Evidence of active infection • Documented current central nervous system involvement by leukemia or lymphoma
研究者
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