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临床试验/CTRI/2026/01/100634
CTRI/2026/01/100634尚未招募不适用

Management Of Rheumatoid Arthritis By Individualised Homoeopathic Treatment Based on miasmatic Evolution:A Case Series.

Dr Ankita Sandeep Patil1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年1月19日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Miasmatic analysis of Rheumatoid arthritis patient

研究概览

简要总结

Title

Management of Rheumatoid Arthritis by Individualised Homoeopathic Treatment Based on Miasmatic Evolution: A Case Series Study.

Introduction

Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disorder characterized by symmetrical joint involvement, pain, stiffness, deformities, and functional disability. Conventional management provides symptomatic relief but is often associated with adverse effects and does not prevent long-term disease progression. Homoeopathy offers an individualized, holistic approach with emphasis on totality of symptoms and miasmatic background, making it a potential alternative for long-term management of RA.

Research Gap

Limited literature on the role of miasmatic analysis in RA

Lack of studies on individualized homoeopathic treatment in RA

Insufficient evidence on long-term outcomes of homoeopathic management

Poor understanding of psychological and miasmatic influences in RA

Need for systematic clinical evaluation through case series

Review of Literature (Brief)

RA is a chronic inflammatory polyarthritis with extra-articular manifestations and progressive joint damage. It commonly affects women aged 40–60 years. Autoimmunity, genetic predisposition, cytokine imbalance, and environmental factors play a key role in pathogenesis. Homoeopathic literature considers RA as a degenerative disease arising from mixed chronic miasms—mainly psora, sycosis, and syphilis. Previous studies suggest symptomatic improvement with individualized homoeopathic treatment, though evidence remains limited.

Research Question

What is the impact of miasmatic analysis–based individualized homoeopathic management in patients with Rheumatoid Arthritis?

Hypothesis

H1 (Alternative): Miasmatic analysis–based homoeopathic management significantly improves clinical symptoms of Rheumatoid Arthritis.

H0 (Null): Miasmatic analysis–based homoeopathic management has no significant impact on clinical symptoms of Rheumatoid Arthritis.

Objectives

Primary Objective

To analyze the role of individualized homoeopathic treatment in the management of Rheumatoid Arthritis with miasmatic analysis.

Secondary Objectives

To evaluate the efficacy of homoeopathic medicines in reducing pain, inflammation, and improving mobility.

To assess the long-term impact of miasmatic homoeopathic treatment on disease progression and overall health.

Methodology

Study Design: Case series study

Study Setting: Motiwala Homoeopathic Medical College OPD, peripheral OPDs, and camps

Sample Size: 30 cases

Sampling Technique: Simple random sampling

Study Duration: 18 months

Duration per Case: 6 months to 1 year

Follow-up: Every 15 days or as required

Inclusion Criteria

Pre-diagnosed RA patients with RA factor >14 IU/ml

Patients of all ages and both genders

Exclusion Criteria

Severe RA requiring hospitalization

Patients on other systems of treatment

Irregular or non-cooperative patients

Assessment Tools

Homoeopathic case taking proforma

PROM & PREM scale

Visual Analogue Scale (VAS) for pain

Data Analysis

Data will be analyzed using appropriate statistical methods (paired t-test / Wilcoxon test) with significance set at p < 0.05.

Expected Outcome

The study aims to demonstrate that individualized homoeopathic treatment based on miasmatic analysis can effectively reduce symptoms, improve quality of life, and help in long-term management of Rheumatoid Arthritis.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Pre-diagnosed patients of Rheumatoid arthritis with ra factor test positive and more than 14 IU/ml more.
  • Patients of both gender.
  • Patients of all ages.

排除标准

  • Severe cases of Rheumatoid arthritis requring Hospitalization due to emergency crisis.

结局指标

主要结局

Miasmatic analysis of Rheumatoid arthritis patient

时间窗: baseline

次要结局

  • improvement in daily functioning, reduction in pain episodes & flare-ups, decreased dependency on other medicines, & overall well-being.(After 6 month)

研究者

发起方
Dr Ankita Sandeep Patil
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Ankita Sandeep Patil

Motiwala Homoeopathic National Medical College

研究点 (1)

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