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Clinical Trials/NCT06759454
NCT06759454
Not yet recruiting
Not Applicable

Comparison of Mean Pain Score Using LASER Therapy and Desensitizing Agents in Patients With Dentinal Hypersensitivity: A Randomized Controlled Trial

Kemia Gul1 site in 1 country172 target enrollmentJune 30, 2025

Overview

Phase
Not Applicable
Intervention
Glutaraldehyde-Based Desensetizing Agent
Conditions
Dentinal Hypersensitivity
Sponsor
Kemia Gul
Enrollment
172
Locations
1
Primary Endpoint
Change in pain intensity: Visual Analog Scale
Status
Not yet recruiting
Last Updated
11 months ago

Overview

Brief Summary

This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)

Detailed Description

This study examines dentinal hypersensitivity treatment modalities, including laser therapy and desensitizing agents. The study is conducted in compliance with regional ethical guidelines

Registry
clinicaltrials.gov
Start Date
June 30, 2025
End Date
June 30, 2026
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kemia Gul
Responsible Party
Sponsor Investigator
Principal Investigator

Kemia Gul

Comparison of Mean Pain Score Using Laser Therapy and Desensitizing Agents in Patients with Dentinal Hypersensitivity: A Randomized Controlled Trial

College of Physicians and Surgeons Pakistan

Eligibility Criteria

Inclusion Criteria

  • Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity.
  • Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion.
  • Participants with good systemic health.
  • Minimum of two hypersensitive teeth present in two different quadrants.

Exclusion Criteria

  • Teeth with caries, defective restorations, or cervical defects \> 2 mm (may affect sensitivity measurements).
  • Periodontal surgery or deep periodontal pockets (\> 6 mm) within the past three months (potential influence on periodontal health and sensitivity).
  • Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes).
  • Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status).
  • Pregnant or lactating women (hormonal changes can influence oral health).

Arms & Interventions

Arm 1 (Desensitizing Agent)

A glutaraldehyde-based desensitizing agent applied to affected teeth for 30 seconds, air-dried, with post-application instructions

Intervention: Glutaraldehyde-Based Desensetizing Agent

Arm 2 (Laser Therapy)

Diode laser set to 100 mW in continuous wave mode, applied to specific areas of affected teeth for three minutes

Intervention: Low Level Laser Therapy

Outcomes

Primary Outcomes

Change in pain intensity: Visual Analog Scale

Time Frame: Immediately post-treatment, one week, and three months

After intervention there is a possibility of change in pain intensity in Dentinal Hypersensitivity

Study Sites (1)

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