Standardizing Emergency Work-ups Around Risk Data (STEWARD): The CREST Network Chest Pain Project
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Kaiser Permanente
- Enrollment
- 13,419
- Locations
- 12
- Primary Endpoint
- Major adverse cardiac event (MACE)
Study Overview
Brief Summary
Chest pain is the second leading reason for emergency department (ED) visits in the United States. Resource utilization for this ED subpopulation is particularly high, in part due to a dearth of accepted standardized clinical approaches and general overestimation of risk on the part of both providers and patients. This prospective observational cohort study seeks to address this issue by providing externally validated risk scores for major adverse cardiac events using a web-based clinical decision support platform (RISTRA) embedded within the electronic health record at 13 Kaiser Permanente Northern California (KPNC) EDs over a 12-month period. The decision support will provide risk estimates specific to the KPNC patient population. This studies hypothesis is that the provision of more accurate risk estimation for major adverse cardiac events will improve informed decision making by both providers and patients, resulting in less provocative testing and lower ED lengths of stay amongst low risk patients, as well as improving medical management among non-low risk patients and decreasing future rates of major adverse cardiac events.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Emergency department chief complaint of chest pain or chest discomfort
- •Clinical concern for possible cardiac ischemia
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Major adverse cardiac event (MACE)
Time Frame: 12 months
A composite outcome of either acute myocardial infarction, cardiac arrest, malignant arrhythmia, cardiac-related mortality
Secondary Outcomes
- Provocative and anatomic cardiac testing rates(12 months)
- Emergency department length of stay(12 months)
- Hospital admission rate(12 months)
