跳至主要内容
临床试验/CTRI/2023/11/060308
CTRI/2023/11/060308尚未招募不适用

Comparative efficacy of different concentration of topical tazarotene and topical tretinoin in acne vulgaris.

Department of Dermatology1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2023年12月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1
主要终点
1. To compare the clinical efficacy of topical 0.025% and 0.05% tretinoin with 0.05% and 0.1% tazarotene in acne vulgaris.

研究概览

简要总结

Various studies have been conducted in past comparing different topical agents belonging to different groups for acne vulgaris. Despite this, there is lack of data comparing efficacy of different concentration of topical retinoids. This study aims at comparing the clinical efficacy of topical 0.025% and 0.05% tretinoin with 0.05% and 0.1% tazarotene in acne vulgaris as there are no studies in literature comparing the efficacy of these four topical retinoids with each other.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Patients of acne vulgaris (Grade 1 & 2) involving face and not requiring systemic therapy.
  • Patients of 18-50 years of age.

排除标准

  • Pregnant and lactating mothers
  • Patients having any systemic illness requiring drugs
  • Patients with signs and symptoms of hyperandrogenism.

结局指标

主要结局

1. To compare the clinical efficacy of topical 0.025% and 0.05% tretinoin with 0.05% and 0.1% tazarotene in acne vulgaris.

时间窗: 2nd, 4th, 6th and 8th week

次要结局

  • 2. To assess and compare the adverse effects of these therapeutic agents.(2nd, 4th, 6th and 8th week)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Sunidhi Sharma

Government Medical College and Hospital, Chandigarh

研究点 (1)

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