Copeptin After Arginine Infusion in Polyuria-Polydipsia Syndrome
Completed
- Conditions
- Polyuria-polydipsia SyndromeHealthy
- Registration Number
- NCT01879137
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Brief Summary
the purpose of the study is to investigate whether arginine infusion is a new tool to differentiate patients with diabetes insipidus, primary polydipsia and healthy subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Age over 18 years
- No medication except hormonal contraception
Exclusion Criteria
- Evidence of any acute illness
- Subjects refusing or unable to give written informed consent
- Pregnancy
- Any evidence of disordered drinking habits and diuresis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Discriminative value of copeptin after arginine infusion in the differential diagnosis of polyuria-polydipsia syndrome. up to 120 minutes after the Arginine infusion.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie copeptin release after arginine infusion in diabetes insipidus patients?
How does arginine infusion compare to standard-of-care tests for diagnosing polyuria-polydipsia syndrome?
Are copeptin levels reliable biomarkers for differentiating primary polydipsia from diabetes insipidus?
What adverse events are associated with arginine infusion in the CARGO-Study and how are they managed?
What other compounds or biomarkers are being explored for differential diagnosis of polyuria-polydipsia syndrome?
Trial Locations
- Locations (1)
University Hospital Basel
🇨🇭Basel, Basel-Stadt, Switzerland
University Hospital Basel🇨🇭Basel, Basel-Stadt, Switzerland