Moxibustion for pre & stage 1 hypertension: a pilot randomized controlled open trial

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 45

Inclusion Criteria

1. patient age between 19 and 65 years
2. Prehypertension or stage 1 hypertension(JNC 7)
3. patients voluntarily participated in this experiment and signed the consent form

Exclusion Criteria

1. Those who are taking prescriptions or OTC medications or herb/supplements in order to control their blood pressure
2. Second stage hypertension patients
3. Personal history, such as cerebrovascular diseases and cardiovascular diseases (myocardial infarction, angina pectoris, valvular heart disease, etc.)
4. History of vicious tumor
5. Diabetic patients taking insulin or anti-diabetic medications
6. Those with history of kidney, liver, thyroid gland diseases
7. Those with hemorrhagic diseases or taking anticoagulation medications(excluding aspirin)
8. Those dependent on drugs or addicted to alcohol
9. Those with active tuberculosis or other infectious diseases
10. Those who have had hypersensitivity reactions following moxibustion
11. Those who are receiving systemic steroid therapy or immunosuppressive drug therapy
12. Those who have taken drugs that affect blood pressure in the past week or who have been taking them for a while, such as oral birth control pills, central nervous system depressants, or stimulants
13. Pregnant mothers, lactating women and those planning for pregnancy
14. Those who have received oriental medicine treatment related to hypertension in the past month
15. Those who are deemed not to be suitable as judged by the person in charge of carrying out the clinical trial

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
blood pressure before and after moxibustion treatment

Secondary Outcome Measures

Name	Time	Method
mean of pulse pressure;BMI(Body Mass Index);blood test(FBS, uric acid, lipid profile, hs CRP, LFT, HbA1C, CBC);HRV(Heart Rate Variability);Modified form of the Stress Response Inventory (SRI-MF);Pittsburgh Sleep Quality Index(PSQI);Fatigue Severity Scale (FSS);EuroQol(EQ-5D) ;General assessment;Questionnaire of Pattern Identification;Neck Disability Index(NDI)